Spinal cord stimulation in experimental chronic painful diabetic polyneuropathy: Delayed effect of High-frequency stimulation

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Spinal cord stimulation in experimental chronic painful diabetic polyneuropathy: Delayed effect of High‐frequency stimulation

BACKGROUND Spinal cord stimulation (SCS) has been shown to provide pain relief in painful diabetic polyneuropathy (PDPN). As the vasculature system plays a great role in the pathophysiology of PDPN, a potential beneficial side-effect of SCS is peripheral vasodilation, with high frequency (HF) SCS in particular. We hypothesize that HF-SCS (500 Hz), compared with conventional (CON) or low frequen...

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Pain relief and quality-of-life improvement after spinal cord stimulation in painful diabetic polyneuropathy: a pilot study.

BACKGROUND Painful diabetic polyneuropathy (PDP) is associated with high pain scores and is difficult to treat. Therefore, spinal cord stimulation (SCS) has been suggested as second-line treatment. In this study, the feasibility and efficacy of SCS in PDP were investigated, as well as the predictive value of clinical sensory testing for the treatment outcome. METHODS Fifteen patients with int...

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Spinal cord stimulation: does frequency matter?

243 August 2013 S PINAL cord stimulation was first described in 1967 in an intriguing case report provided by Shealy et al.1 This first case involved the relief from cancerrelated pain using a surgically implanted electrode sutured to the dura to provide stimulation of the dorsal columns. Although the entire treatment was only for approximately 1 day before the patient’s demise, stimulation usi...

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Spinal cord stimulation in patients with painful diabetic neuropathy: a multicentre randomized clinical trial.

Painful diabetic neuropathy (PDN) is a peripheral neuropathic pain condition that is often difficult to relieve. Spinal cord stimulation (SCS) is a proven effective therapy for various types of mixed neuropathic conditions, yet effectiveness of SCS treatment for PDN is not well established. To our knowledge, ours is the first multicentre randomized controlled trial investigating the effectivene...

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ژورنال

عنوان ژورنال: European Journal of Pain

سال: 2016

ISSN: 1090-3801

DOI: 10.1002/ejp.981